Nachdem der totgeglaubte Mutanten-Killer Popeye von einer Sondereinheit gefangen und mit einem Supersoldaten-Serum injiziert wird, bricht er aus und hinterlässt in einem nahegelegenen Sommercamp ein blutiges Massaker.

The monstrous killer sailor returns in an even more lethal form. After being captured by a ruthless military task force, Popeye is subjected to a super-soldier experiment that amplifies his brute strength to unimaginable levels. Breaking free from confinement, his violent path leads straight to a nearby summer camp, where a group of unsuspecting counselors must face an unstoppable, serum-fueled killing machine.